Ungiminorine
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| Names
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| IUPAC name
(1S,16R,17R,18S,19S)-17-methoxy-5,7-dioxa-12-azapentacyclo[10.6.1.02,10.04,8.015,19]nonadeca-2,4(8),9,14-tetraene-16,18-diol
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| Identifiers
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| ChEMBL
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| ChemSpider
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InChI=1S/C17H19NO5/c1-21-17-15(19)9-2-3-18-6-8-4-11-12(23-7-22-11)5-10(8)13(14(9)18)16(17)20/h2,4-5,13-17,19-20H,3,6-7H2,1H3/t13-,14+,15+,16-,17-/m0/s1 Key: ZQLQBAUVRGDBJL-BIVLZKPYSA-N InChI=1/C17H19NO5/c1-21-17-15(19)9-2-3-18-6-8-4-11-12(23-7-22-11)5-10(8)13(14(9)18)16(17)20/h2,4-5,13-17,19-20H,3,6-7H2,1H3/t13-,14+,15+,16-,17-/m0/s1 Key: ZQLQBAUVRGDBJL-BIVLZKPYBI
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CO[C@@H]1[C@H]([C@@H]2[C@H]3C(=CCN3CC4=CC5=C(C=C24)OCO5)[C@H]1O)O
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Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
Infobox references
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Ungiminorine is an acetylcholinesterase inhibitor isolated from Narcissus.[1]
References
- ^ Ingkaninan, K.; Hazekamp, A.; de Best, C. M.; Irth, H.; Tjaden, U. R.; van der Heijden, R.; van der Greef, J.; Verpoorte, R. (June 2000). "The application of HPLC with on-line coupled UV/MS-biochemical detection for isolation of an acetylcholinesterase inhibitor from narcissus 'Sir Winston Churchill'". Journal of Natural Products. 63 (6): 803–806. doi:10.1021/np9905719. ISSN 0163-3864. PMID 10869205.
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Enzyme (modulators) | | ChATTooltip Choline acetyltransferase |
- Inhibitors: 1-(-Benzoylethyl)pyridinium
- 2-(α-Naphthoyl)ethyltrimethylammonium
- 3-Chloro-4-stillbazole
- 4-(1-Naphthylvinyl)pyridine
- Acetylseco hemicholinium-3
- Acryloylcholine
- AF64A
- B115
- BETA
- CM-54,903
- N,N-Dimethylaminoethylacrylate
- N,N-Dimethylaminoethylchloroacetate
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| AChETooltip Acetylcholinesterase | |
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| BChETooltip Butyrylcholinesterase | |
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Transporter (modulators) | | CHTTooltip Choline transporter | |
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| VAChTTooltip Vesicular acetylcholine transporter | |
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Release (modulators) | |
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- See also
- Receptor/signaling modulators
- Muscarinic acetylcholine receptor modulators
- Nicotinic acetylcholine receptor modulators
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