Thiobuscaline

Thiobuscaline
Clinical data
Other names	4-Butylthio-3,5-dimethoxyphenethylamine; 3,5-Dimethoxy-4-butylthiophenethylamine
Routes of; administration	Oral
ATC code	None;
Pharmacokinetic data
Duration of action	8 hours
Identifiers
	IUPAC name 2-[4-(butylsulfanyl)-3,5-dimethoxyphenyl]ethan-1-amine;
CAS Number	90109-57-2 ;
PubChem CID	44349865;
ChemSpider	21106390 ;
UNII	45ZTS7GX2F;
ChEMBL	ChEMBL123840 ;
CompTox Dashboard (EPA)	DTXSID80658366 ;
Chemical and physical data
Formula	C14H23NO2S
Molar mass	269.40 g·mol−1
3D model (JSmol)	Interactive image;
	SMILES COc1cc(cc(OC)c1SCCCC)CCN;
	InChI InChI=1S/C14H23NO2S/c1-4-5-8-18-14-12(16-2)9-11(6-7-15)10-13(14)17-3/h9-10H,4-8,15H2,1-3H3 ; Key:CPNWMHCBHUXITO-UHFFFAOYSA-N ;
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Thiobuscaline, or 3,5-dimethoxy-4-butylthiophenethylamine, is a lesser-known psychedelic drug of the scaline family.^[2] It is an analog of buscaline.^[2] Thiobuscaline was first synthesized by Alexander Shulgin.^[3] In his book PiHKAL (Phenethylamines i Have Known And Loved), the dose range is listed as 60–120 mg, and the duration is listed as 8 hours.^[1] Thiobuscaline is an entheogen, and it causes a threshold. Very little data exists about the pharmacological properties, metabolism, and toxicity of thiobuscaline.

References

^ ^a ^b ^c Shulgin AT, Shulgin A (1991). PiHKAL: A Chemical Love Story (1st ed.). Berkeley, CA: Transform Press. ISBN 978-0-9630096-0-9. OL 22859055M.
^ ^a ^b McCreary AC, Müller CP, Filip M (2015-06-05). "Psychostimulants: basic and clinical pharmacology.". In Taba P, Lees AJ, Sikk K (eds.). The Neuropsychiatric Complications of Stimulant Abuse. Academic Press. ISBN 978-0-12-803003-5.
^ Baumann MH, Ayestas MA, Partilla JS, Sink JR, Shulgin AT, Daley PF, et al. (April 2012). "The designer methcathinone analogs, mephedrone and methylone, are substrates for monoamine transporters in brain tissue". Neuropsychopharmacology. 37 (5): 1192–1203. doi:10.1038/npp.2011.304. PMC 3306880. PMID 22169943.

[Shulgin_1991-1] Shulgin AT, Shulgin A (1991). PiHKAL: A Chemical Love Story (1st ed.). Berkeley, CA: Transform Press. ISBN 978-0-9630096-0-9. OL 22859055M.

[McCreary_2015-2] McCreary AC, Müller CP, Filip M (2015-06-05). "Psychostimulants: basic and clinical pharmacology.". In Taba P, Lees AJ, Sikk K (eds.). The Neuropsychiatric Complications of Stimulant Abuse. Academic Press. ISBN 978-0-12-803003-5.

[3] Baumann MH, Ayestas MA, Partilla JS, Sink JR, Shulgin AT, Daley PF, et al. (April 2012). "The designer methcathinone analogs, mephedrone and methylone, are substrates for monoamine transporters in brain tissue". Neuropsychopharmacology. 37 (5): 1192–1203. doi:10.1038/npp.2011.304. PMC 3306880. PMID 22169943.

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[2]

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See also

References