6-EAPB

6-EAPB
Legal status
Legal status
Identifiers
  • 1-(benzofuran-6-yl)-N-ethylpropan-2-amine
CAS Number
ChemSpider
UNII
Chemical and physical data
FormulaC13H17NO
Molar mass203.285 g·mol−1
3D model (JSmol)
  • CCNC(CC1=CC2=C(C=CO2)C=C1)C
  • InChI=1S/C13H17NO.ClH/c1-3-14-10(2)8-11-4-5-12-6-7-15-13(12)9-11;/h4-7,9-10,14H,3,8H2,1-2H3;1H
  • Key:MUFUSNCKTVRMLR-UHFFFAOYSA-N

6-EAPB, also known as 1-(benzofuran-6-yl)-N-ethylpropan-2-amine, is a potentially psychedelic and potentially entactogenic drug of the benzofuran class;[1] it is structurally related to 6-APB and MDMA.

Pharmacology

Pharmacodynamics

6-EAPB is a potent monoamine reuptake inhibitor.[2] It shows very low potency as a serotonin 5-HT2A receptor agonist.[2]

Society and culture

As an N-ethyl derivative of 6-APB, 6-EAPB fell outside the scope of the Temporary Class Drug ban issued by the Home Office on June 10, 2013.[3] The ACMD has advised that 6-EAPB (and other benzofurans) are moved to Class B,[4] this came into action on 10 June 2014.[5]

See also

References

  1. ^ Taschwer M, Hofer MG, Schmid MG (October 2014). "Enantioseparation of benzofurys and other novel psychoactive compounds by CE and sulfobutylether β-cyclodextrin as chiral selector added to the BGE". Electrophoresis. 35 (19): 2793–2799. doi:10.1002/elps.201400164. PMID 24930967. S2CID 2937770.
  2. ^ a b Stalberga, D., Kronstrand, R., Schranz, B., van Zijl, N., Karlman, S., Aref, S., ... & Gréen, H. (2025). Comprehensive in vitro profiling of traditional and emerging stimulants at monoamine transporters and the 5HT2A receptor. https://doi.org/10.22541/au.176253891.19158813/v1
  3. ^ "Temporary class drug order on benzofury and NBOMe compounds". Retrieved 15 June 2015.
  4. ^ "ACMD recommends permanent ban on two "legal highs"". Retrieved 15 June 2015.
  5. ^ "Ban on NBOMe and benzofurans comes into force". Retrieved 15 June 2015.


This article is issued from Wikipedia. The text is available under Creative Commons Attribution-Share Alike 4.0 unless otherwise noted. Additional terms may apply for the media files.