4,5-MDO-DiPT

4,5-MDO-DiPT
Clinical data
Other names4,5-Methylenedioxy-N,N-diisopropyltryptamine
Routes of
administration		Oral[1]
Drug classSerotonergic psychedelic; Hallucinogen
ATC code
  • None
Pharmacokinetic data
Duration of actionUnknown[1]
Identifiers
  • N-[2-(6H-[1,3]dioxolo[4,5-e]indol-8-yl)ethyl]-N-propan-2-ylpropan-2-amine
CAS Number
PubChem CID
ChemSpider
UNII
ChEMBL
CompTox Dashboard (EPA)
Chemical and physical data
FormulaC17H24N2O2
Molar mass288.391 g·mol−1
3D model (JSmol)
  • CC(C)N(CCC1=CNC2=C1C3=C(C=C2)OCO3)C(C)C
  • InChI=1S/C17H24N2O2/c1-11(2)19(12(3)4)8-7-13-9-18-14-5-6-15-17(16(13)14)21-10-20-15/h5-6,9,11-12,18H,7-8,10H2,1-4H3
  • Key:PTYYWSKZYOSFEK-UHFFFAOYSA-N

4,5-MDO-DiPT, also known as 4,5-methylenedioxy-N,N-diisopropyltryptamine, is a lesser-known psychedelic drug of the tryptamine family.[1] It is the 4,5-methylenedioxy derivative of diisopropyltryptamine (DiPT) and is an analogue of 4-HO-DiPT and 5-MeO-DiPT.[1]

Use and effects

In his book TiHKAL (Tryptamines I Have Known and Loved), Alexander Shulgin lists the dose of 4,5-MDO-DiPT as greater than 25 mg orally, whereas the duration is listed as unknown.[1] At a dose of 25 mg, nothing happened for 3 hours, then the drug suddenly onset and produced LSD-like psychedelic effects, with a plateau that lasted for a fair amount of time.[1] Higher doses were not explored.[1]

Interactions

See also: Psychedelic drug § Interactions, and Trip killer § Serotonergic psychedelic antidotes

Pharmacology

Very little data exists about the pharmacological properties, metabolism, and toxicity of 4,5-MDO-DiPT.[1]

Chemistry

Synthesis

The chemical synthesis of 4,5-MDO-DiPT has been described.[1]

Analogues

Analogues of 4,5-MDO-DiPT include diisopropyltryptamine (DiPT), 4-HO-DiPT, 5-MeO-DiPT, 4,5-MDO-DMT, 5,6-MDO-DiPT, and 4,5-DHP-DMT, among others.[1]

History

4,5-MDO-DiPT was first described in the scientific literature by Toni B. Kline and colleagues in 1982.[2] Subsequently, it was further described by Alexander Shulgin in his 1997 book TiHKAL (Tryptamines I Have Known and Loved).[1]

See also

References

  1. ^ a b c d e f g h i j k Shulgin, Alexander; Shulgin, Ann (September 1997). TiHKAL: The Continuation. Berkeley, California: Transform Press. ISBN 0-9630096-9-9. OCLC 38503252.
  2. ^ Kline TB, Benington F, Morin RD, Beaton JM (August 1982). "Structure-activity relationships in potentially hallucinogenic N,N-dialkyltryptamines substituted in the benzene moiety". J Med Chem. 25 (8): 908–913. doi:10.1021/jm00350a005. PMID 7120280.
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