vedotin
English
Noun
vedotin (uncountable)
- (pharmacology) the compound monomethyl auristatin E, when bound to a monoclonal antibody.
- 2010 May, Kelley V. Foyil, Nancy L. Bartlett, “Anti-CD30 Antibodies for Hodgkin lymphoma”, in Current Hematologic Malignancy Reports, volume 5, :
- One highly active ADC, brentuximab vedotin (SGN-35), combines an anti-CD30 monoclonal antibody and the antitubulin agent monomethyl auristatin E.