Down syndrome

• Down’s syndrome (chiefly in the UK and rarely Canada)

Named after John Langdon Haydon Down (1828–1896), an English physician who first described the condition as a distinct form of mental disability in the 1860s.

• (Received Pronunciation) IPA^(key): /daʊn ˈsɪndɹəʊm/
• (General American) IPA^(key): /daʊn ˈsɪndɹoʊm/, /-dɹəm/

• Audio (General Australian):

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• Hyphenation: Down syn‧drome

Down syndrome (uncountable) (chiefly US, Ireland, Australia, New Zealand, usually Canada)

2. (neurology, medical genetics) A genetic disorder caused by the presence of all or part of a third copy of chromosome 21 (a chromosomal excess), whereby the patients typically have a delay in cognitive ability and physical growth, as well as a small head and tilted eyelids. [from 1961.]

   Synonyms: Down's (informal), mongolism (offensive), Mongolian idiocy (offensive), trisomy 21

• Down's syndrome is the standard term in the UK, and is occasionally used in Canada.

• Down syndrome on Wikipedia.Wikipedia