Vidarabine phosphate

Vidarabine phosphate
Names
IUPAC name
(1R)-1-(6-Amino-9H-purin-9-yl)-1,4-anhydro-1-deoxy-β-D-arabinitiol 5-(dihydrogen phosphate)
Systematic IUPAC name
[(2R,3S,4S,5R)-5-(6-Amino-9H-purin-9-yl)-3,4-dihydroxyoxolan-2-yl]methyl dihydrogen phosphate
Identifiers
3D model (JSmol)
ChEBI
ChemSpider
ECHA InfoCard 100.045.431
MeSH Vidarabine+phosphate
UNII
  • InChI=1S/C10H14N5O7P/c11-8-5-9(13-2-12-8)15(3-14-5)10-7(17)6(16)4(22-10)1-21-23(18,19)20/h2-4,6-7,10,16-17H,1H2,(H2,11,12,13)(H2,18,19,20)/t4-,6-,7+,10-/m1/s1 N
    Key: UDMBCSSLTHHNCD-UHTZMRCNSA-N N
  • InChI=1/C10H14N5O7P/c11-8-5-9(13-2-12-8)15(3-14-5)10-7(17)6(16)4(22-10)1-21-23(18,19)20/h2-4,6-7,10,16-17H,1H2,(H2,11,12,13)(H2,18,19,20)/t4-,6-,7+,10-/m1/s1
    Key: UDMBCSSLTHHNCD-UHTZMRCNBN
  • c1nc(c2c(n1)n(cn2)[C@H]3[C@H]([C@@H]([C@H](O3)COP(=O)(O)O)O)O)N
Properties
C10H14N5O7P
Molar mass 347.221221
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
N verify (what is YN ?)
Infobox references

Vidarabine phosphate is an adenosine monophosphate nucleotide in which ribose is replaces by an arabinose moiety. It is the monophosphate ester of vidarabine, with antiviral and possibly antineoplastic properties.[1] It has displayed activity against chronic hepatitis B infection.[2]

See also

References

  1. ^ PubChem
  2. ^ Smith, C. I.; Kitchen, L. W.; Scullard, G. H.; Robinson, W. S.; Gregory, P. B.; Merigan, T. C. (1982-04-23). "Vidarabine monophosphate and human leukocyte interferon in chronic hepatitis B infection". JAMA. 247 (16): 2261–2265. ISSN 0098-7484. PMID 6175774.


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