Steven McCarroll
Steven A. McCarroll | |
|---|---|
| Born | Steven Andrew McCarroll |
| Education |
|
| Scientific career | |
| Fields | Genetics, Neuroscience |
| Institutions | Harvard Medical School, Broad Institute, HHMI |
| Thesis | The statistical and molecular logic of gene expression patterns in Caenorhabditis elegans (2004) |
| Doctoral advisor | Cori Bargmann |
| Other academic advisors | David Altshuler, Mark Daly |
| Website | McCarroll Lab |
Steven A. McCarroll is an American geneticist and neuroscientist who is the Dorothy and Milton Flier Professor of Biomedical Science and Genetics at Harvard Medical School. He is also an institute member of the Broad Institute and an HHMI investigator.
Biography
McCarroll earned a B.A. in economics from Stanford University in 1993.[1] He received a Ph.D. in neuroscience from the University of California, San Francisco in 2004, where he worked in the lab of Cori Bargmann.[2] Following his Ph.D., McCarroll worked as a postdoctoral fellow with David Altshuler and Mark Daly at Massachusetts General Hospital and the Broad Institute.[3]
Research
McCarroll's lab studies natural variation in the human brain and the ways in which genes and genetic variation shape the brain's functions and vulnerabilities.[4] Research in his lab has explained the contribution of variation in complement component 4 to schizophrenia risk[5] and revealed a mechanism by which CAG repeat expansion may drive neurodegeneration in Huntington's disease.[6]
References
- ^ Sam Scott (July 2015). "A New Kind of Martian". Stanford Magazine. Retrieved October 26, 2025.
- ^ "People". McCarroll Lab. Retrieved October 26, 2025.
- ^ "Steven McCarroll, PhD". Simons Foundation. Retrieved October 26, 2025.
- ^ "Steve McCarroll, PhD". Broad Institute Center for Human Brain Function. Retrieved October 26, 2025.
- ^ Sekar A, Bialas AR, de Rivera H, Davis A, Hammond TR, Kamitaki N, Tooley K, Presumey J, Baum M, Van Doren V, Genovese G, Rose SA, Handsaker RE, Daly MJ, Carroll MC, Stevens B, McCarroll SA (January 27, 2016). "Schizophrenia risk from complex variation of complement component 4". Nature. 530 (7589): 577–583. doi:10.1038/nature16549. Retrieved October 26, 2025.
- ^ Handsaker RE, Kashin S, Reed NM, Tan S, Lee WS, McDonald TM, Morris K, Kamitaki N, Mullally CD, Morakabati NR, Goldman M, Lind G, Kohli R, Lawton E, Hogan M, Ichihara K, Berretta S, McCarroll SA (February 6, 2025). "Long somatic DNA-repeat expansion drives neurodegeneration in Huntington's disease". Cell. 188 (3): 623–639. doi:10.1016/j.cell.2024.11.038. Retrieved October 26, 2025.
External links
- Steven McCarroll publications indexed by Google Scholar