Sequoyitol dehydrogenase

sequoyitol dehydrogenase
Identifiers
EC no.1.1.1.143
CAS no.37250-72-9
Databases
IntEnzIntEnz view
BRENDABRENDA entry
ExPASyNiceZyme view
KEGGKEGG entry
MetaCycmetabolic pathway
PRIAMprofile
PDB structuresRCSB PDB PDBe PDBsum
Gene OntologyAmiGO / QuickGO
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PMCarticles
PubMedarticles
NCBIproteins

In enzymology, sequoyitol dehydrogenase (EC 1.1.1.143) is an enzyme that catalyzes the chemical reaction

sequoyitol
 
 
 
H+
 
H+
 
2D-5-O-methyl-2,3,5/4,6-pentahydroxycyclohexanone
 

The two substrates of this enzyme are sequoyitol and oxidised nicotinamide adenine dinucleotide (NAD+). Its products are 2D-5-O-methyl-2,3,5/4,6-pentahydroxycyclohexanone, reduced NADH, and a proton.[1][2]

This enzyme belongs to the family of oxidoreductases, specifically those acting on the CH-OH group of donor with NAD+ or NADP+ as acceptor. The systematic name of this enzyme class is 5-O-methyl-myo-inositol:NAD+ oxidoreductase. This enzyme is also called D-pinitol dehydrogenase.

References

  1. ^ Enzyme 1.1.1.143 at KEGG Pathway Database.
  2. ^ Ruis H, Hoffmann-Ostenhof O (1969). "Enzymic epimerization of sequoyitol to D-pinitol in Trifolium incarnatum". Eur. J. Biochem. 7 (3): 442–8. doi:10.1111/j.1432-1033.1969.tb19629.x. PMID 4389340.