Ribose 1-dehydrogenase (NADP+)
| ribose 1-dehydrogenase (NADP+) | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifiers | |||||||||
| EC no. | 1.1.1.115 | ||||||||
| CAS no. | 37250-46-7 | ||||||||
| Databases | |||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB structures | RCSB PDB PDBe PDBsum | ||||||||
| Gene Ontology | AmiGO / QuickGO | ||||||||
| |||||||||
In enzymology, ribose 1-dehydrogenase (NADP+) (EC 1.1.1.115) is an enzyme that catalyzes the chemical reaction
The three substrates of this enzyme are D-ribose, oxidised nicotinamide adenine dinucleotide phosphate (NADP+), and water. Its products are D-ribonic acid, reduced NADPH, and a proton.[1][2][3]
This enzyme belongs to the family of oxidoreductases, specifically those acting on the CH-OH group of donor with NAD+ or NADP+ as acceptor. The systematic name of this enzyme class is D-ribose:NADP+ 1-oxidoreductase. Other names in common use include D-ribose dehydrogenase (NADP+), NADP+-pentose-dehydrogenase, and ribose 1-dehydrogenase (NADP+).
References
- ^ Enzyme 1.1.1.115 at KEGG Pathway Database.
- ^ Scher BM, Horecker BL (1966). "Pentose metabolism in Candida. 3. The triphosphopyridine nucleotide-specific polyol dehydrogenase of Candida utilis". Arch. Biochem. Biophys. 116 (1): 117–28. doi:10.1016/0003-9861(66)90020-8. PMID 4381350.
- ^ Schiwara HW, Domschke W, Domagk GF (1968). "[Sugar dehydrogenases in mammalian liver. I. Differentiation of various sugar dehydrogenases from pig liver by disc electrophoresis and ion exchange chromatography]". Hoppe-Seyler's Z. Physiol. Chem. 349 (11): 1575–81. doi:10.1515/bchm2.1968.349.2.1575. PMID 4393642.