RNA-binding protein 12 is a protein that in humans is encoded by the RBM12 gene.[5][6]
This gene encodes a protein that contains several RNA-binding motifs, potential transmembrane domains, and proline-rich regions. This gene and the gene for copine I overlap at map location 20q11.21. Alternative splicing in the 5' UTR results in two transcript variants. Both variants encode the same protein.[6]
References
- ^ a b c GRCh38: Ensembl release 89: ENSG00000244462 – Ensembl, May 2017
- ^ a b c GRCm38: Ensembl release 89: ENSMUSG00000089824 – Ensembl, May 2017
- ^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
- ^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
- ^ Stover C, Gradl G, Jentsch I, Speicher MR, Wieser R, Schwaeble W (Jul 2001). "cDNA cloning, chromosome assignment, and genomic structure of a human gene encoding a novel member of the RBM family". Cytogenetics and Cell Genetics. 92 (3–4): 225–230. doi:10.1159/000056908. PMID 11435693. S2CID 20555964.
- ^ a b "Entrez Gene: RBM12 RNA binding motif protein 12".
Further reading
- Nakajima D, Okazaki N, Yamakawa H, Kikuno R, Ohara O, Nagase T (June 2002). "Construction of expression-ready cDNA clones for KIAA genes: manual curation of 330 KIAA cDNA clones". DNA Research. 9 (3): 99–106. doi:10.1093/dnares/9.3.99. PMID 12168954.
- Olsen JV, Blagoev B, Gnad F, Macek B, Kumar C, Mortensen P, et al. (November 2006). "Global, in vivo, and site-specific phosphorylation dynamics in signaling networks". Cell. 127 (3): 635–648. doi:10.1016/j.cell.2006.09.026. PMID 17081983. S2CID 7827573.
- Kofler M, Motzny K, Freund C (November 2005). "GYF domain proteomics reveals interaction sites in known and novel target proteins". Molecular & Cellular Proteomics. 4 (11): 1797–1811. doi:10.1074/mcp.M500129-MCP200. PMID 16120600.
- Brill LM, Salomon AR, Ficarro SB, Mukherji M, Stettler-Gill M, Peters EC (May 2004). "Robust phosphoproteomic profiling of tyrosine phosphorylation sites from human T cells using immobilized metal affinity chromatography and tandem mass spectrometry". Analytical Chemistry. 76 (10): 2763–2772. doi:10.1021/ac035352d. PMID 15144186.
- Ueki N, Oda T, Kondo M, Yano K, Noguchi T, Muramatsu M (December 1998). "Selection system for genes encoding nuclear-targeted proteins". Nature Biotechnology. 16 (13): 1338–1342. doi:10.1038/4315. PMID 9853615. S2CID 20001769.
External links
PDB gallery |
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1wel: Solution structure of RNA binding domain in NP_006038
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2cpy: solution structure of RNA binding domain 3 in RNA binding motif protein 12
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2cqp: Solution structure of the RNA binding domain of RNA-binding protein 12
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2dnn: Solution structure of RNA binding domain in RNA-binding protein 12
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