Oxaloglycolate reductase (decarboxylating)
| oxaloglycolate reductase (decarboxylating) | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifiers | |||||||||
| EC no. | 1.1.1.92 | ||||||||
| CAS no. | 37250-28-5 | ||||||||
| Databases | |||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB structures | RCSB PDB PDBe PDBsum | ||||||||
| Gene Ontology | AmiGO / QuickGO | ||||||||
| |||||||||
In enzymology, oxaloglycolate reductase (decarboxylating) (EC 1.1.1.92) is an enzyme that catalyzes the chemical reaction
The substrates of this enzyme are D-glyceric acid, oxidised nicotinamide adenine dinucleotide (NAD+), and carbon dioxide. Its products are 2-hydroxy-3-oxosuccinic acid, reduced NADH, and a proton. The enzyme can use the alternative cofactor, nicotinamide adenine dinucleotide phosphate.[1][2]
This enzyme belongs to the family of oxidoreductases, specifically those acting on the CH-OH group of donor with NAD+ or NADP+ as acceptor. The systematic name of this enzyme class is D-glycerate:NAD(P)+ oxidoreductase (carboxylating). This enzyme participates in glyoxylate and dicarboxylate metabolism.
References
- ^ Enzyme 1.1.1.92 at KEGG Pathway Database.
- ^ Kohn LD, Jakoby WB (1968). "Tartaric acid metabolism. VI. Crystalline oxaloglycolate reductive decarboxylase". J. Biol. Chem. 243 (10): 2486–93. doi:10.1016/S0021-9258(18)93401-0. PMID 4385076.