Glycerol-3-phosphate oxidase

glycerol-3-phosphate oxidase
Identifiers
EC no.1.1.3.21
CAS no.9046-28-0
Databases
IntEnzIntEnz view
BRENDABRENDA entry
ExPASyNiceZyme view
KEGGKEGG entry
MetaCycmetabolic pathway
PRIAMprofile
PDB structuresRCSB PDB PDBe PDBsum
Gene OntologyAmiGO / QuickGO
Search
PMCarticles
PubMedarticles
NCBIproteins

In enzymology, glycerol-3-phosphate oxidase (EC 1.1.3.21) is an enzyme that catalyzes the chemical reaction

 
O2
H2O2
O2
H2O2
 

The two substrates of this enzyme are sn-glycerol 3-phosphate and oxygen. Its products are dihydroxyacetone phosphate and hydrogen peroxide.[1][2][3]

This enzyme belongs to the family of oxidoreductases, specifically those acting on the CH-OH group of donor with oxygen as acceptor. The systematic name of this enzyme class is sn-glycerol-3-phosphate:oxygen 2-oxidoreductase. Other names in common use include glycerol phosphate oxidase, glycerol-1-phosphate oxidase, glycerol phosphate oxidase, L-alpha-glycerophosphate oxidase, alpha-glycerophosphate oxidase, and L-alpha-glycerol-3-phosphate oxidase. This enzyme participates in glycerophospholipid metabolism. It employs one cofactor, FAD.

References

  1. ^ Enzyme 1.1.3.21 at KEGG Pathway Database.
  2. ^ Gancedo C, Gancedo JM, Sols A (1968). "Glycerol metabolism in yeasts. Pathways of utilization and production". Eur. J. Biochem. 5 (2): 165–72. doi:10.1111/j.1432-1033.1968.tb00353.x. PMID 5667352.
  3. ^ Koditschek LK, Umbreit WW (1969). "Alpha-glycerophosphate oxidase in Streptococcus faecium F 24". J. Bacteriol. 98 (3): 1063–8. doi:10.1128/jb.98.3.1063-1068.1969. PMC 315296. PMID 5788698.