George Tidmarsh

George Tidmarsh
Director of U.S. Center for Drug Evaluation and Research
In office
July 21, 2025 – November 2, 2025
PresidentDonald Trump
Preceded byJacqueline Corrigan-Curay
Succeeded byRichard Pazdur
temporary Director of U.S. Center for Biologics Evaluation and Research
In office
July 31, 2025 – August 9, 2025
PresidentDonald Trump
Preceded byVinay Prasad
Succeeded byVinay Prasad
Personal details
Born1960 (age 64–65)
Alma materStanford University

George Tidmarsh (born 1960) is an American politician and businessman who served as the Director of U.S. Center for Drug Evaluation and Research from July to October 2025.[1][2] He was also the temporary Director of U.S. Center for Biologics Evaluation and Research after Vinay Prasad resigned,[3] until Prasad returned 10 days later.[4]

Education

Tidmarsh attended Stanford University for his undergraduate degree and subsequently MD and PhD in Cancer Biology.[1][5]

Career

Prior to taking a role in the second Trump administration, Tidmarsh was described as a serial entrepreneur,[5] serving as a founder and executive of several biotech companies.[2] This included bringing Duexis to market as founder and CEO of Horizon Therapeutics,[5] and a subsequent term as CEO of La Jolla Pharmaceutical Company when the company received FDA approval for Giapreza.[6][7]

He was also an adjunct professor at Stanford University School of Medicine and founded a master's degree program in translational research and applied medicine.[2][8]

Controversy

Tidmarsh was placed on administrative leave from the CDER in October 2025 by Marty Makary after accusations of abusing his regulatory authority.[9] A suit was also filed against him by Aurinia Pharmaceuticals claiming Tidmarsh misused his authority to target a businesses of a former associate,[10] and publically questioning the previous FDA approval of its drug voclosporin.[7] On November 2, 2025 Tidmarsh officially resigned from the directorship of the CDER, [11] stating he left to protest the handling of drug reviews at the FDA. [12]

References

  1. ^ a b Tidmarsh, G. (1 July 2013). "Linking academia and industry to bring drugs to the clinic: an interview with George Tidmarsh". Disease Models & Mechanisms. 6 (4): 874–876. doi:10.1242/dmm.012997. PMC 3701206. PMID 23828643.
  2. ^ a b c Annika Kim, Constantino. "FDA taps biotech industry veteran as RFK Jr.'s top drug regulator". No. 21 July 2025. CNBC. Retrieved 5 November 2025.
  3. ^ Kartal Allen, Annabel (31 July 2025). "George Tidmarsh to sub in as FDA CBER head following Prasad's shock exit". Pharmaceutical Technology. Retrieved 5 November 2025.
  4. ^ Weber, Lauren; Roubein, Rachel (August 9, 2025). "FDA regulator reinstalled less than two weeks after White House ouster". thewashingtonpost. Retrieved September 3, 2025.
  5. ^ a b c Parrish, Meaghan; Gibney, Michael (23 July 2025). "Who is Dr. George Tidmarsh, the new director of CDER?". PharmaVoice. Retrieved 7 November 2025.
  6. ^ Dunleavy, Kevin (11 July 2022). "Innoviva snaps up La Jolla and its 2 FDA-approved drugs for $149M". Fierce Pharma. Retrieved 7 November 2025.
  7. ^ a b Kansteiner, Frasier (3 November 2025). "CDER chief George Tidmarsh resigns as deleted LinkedIn post prompts Aurinia lawsuit, FDA probe". Fierce Pharma. Retrieved 5 November 2025.
  8. ^ Council, Stephen (5 November 2025). "Former Stanford professor accused of 'reprehensible' conduct quits top FDA job". SFGate. Retrieved 8 November 2025.
  9. ^ Herper, Matthew; Lawrence, Lizzie (4 November 2025). "Experts worry FDA's credibility is being shredded by scandal and 'soap opera'". Stat News. Retrieved 5 November 2025.
  10. ^ Mole, Beth (4 November 2025). "FDA described as a "clown show" amid latest scandal; top drug regulator is out". Ars Technica. Retrieved 5 November 2025.
  11. ^ Lenzer, Jeanne (7 November 2025). "FDA drug chief resigns amid lawsuit claims of attempting to "extort and solicit a bribe"". theBMJ. Retrieved 11 November 2025.
  12. ^ Gardner, Lauren (21 November 2025). "The White House has asked for the resignation of a top aide to FDA chief". Politico. Retrieved 23 November 2025.