Galactitol 2-dehydrogenase

galactitol 2-dehydrogenase
Identifiers
EC no.1.1.1.16
CAS no.9028-23-3
Databases
IntEnzIntEnz view
BRENDABRENDA entry
ExPASyNiceZyme view
KEGGKEGG entry
MetaCycmetabolic pathway
PRIAMprofile
PDB structuresRCSB PDB PDBe PDBsum
Gene OntologyAmiGO / QuickGO
Search
PMCarticles
PubMedarticles
NCBIproteins

In enzymology, a galactitol 2-dehydrogenase (EC 1.1.1.16) is an enzyme that catalyzes the chemical reaction

 
 
 
H+
 
H+
 
D-tagatose
 

The two substrates of this enzyme are galactitol and oxidised nicotinamide adenine dinucleotide (NAD+). Its products are D-tagatose, reduced NADH, and a proton.[1][2]

This enzyme belongs to the family of oxidoreductases, specifically those acting on the CH-OH group of donor with NAD+ or NADP+ as acceptor. The systematic name of this enzyme class is galactitol:NAD+ 2-oxidoreductase. This enzyme is also called dulcitol dehydrogenase. This enzyme participates in galactose metabolism.

References

  1. ^ Enzyme 1.1.1.16 at KEGG Pathway Database.
  2. ^ Shaw DR (November 1956). "Polyol dehydrogenases. 3. Galactitol dehydrogenase and D-iditol dehydrogenase". The Biochemical Journal. 64 (3): 394–405. doi:10.1042/bj0640394. PMC 1199749. PMID 13373783.