D-iditol 2-dehydrogenase
| d-iditol 2-dehydrogenase | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifiers | |||||||||
| EC no. | 1.1.1.15 | ||||||||
| CAS no. | 9028-22-2 | ||||||||
| Databases | |||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB structures | RCSB PDB PDBe PDBsum | ||||||||
| Gene Ontology | AmiGO / QuickGO | ||||||||
| |||||||||
In enzymology, a d-iditol 2-dehydrogenase (EC 1.1.1.15) is an enzyme that catalyzes the chemical reaction
The two substrates of this enzyme are D-iditol and oxidised nicotinamide adenine dinucleotide (NAD+). Its products are D-sorbose, reduced NADH, and a proton.[1][2]
This enzyme belongs to the family of oxidoreductases, specifically those acting on the CH-OH group of donor with NAD+ or NADP+ as acceptor. The systematic name of this enzyme class is d-iditol:NAD+ 2-oxidoreductase. This enzyme is also called d-sorbitol dehydrogenase. This enzyme participates in pentose and glucuronate interconversions and fructose and mannose metabolism.
See also
References