Clobetasone butyrate

Clobetasone butyrate
Clinical data
Drug classCorticosteroid; Glucocorticoid
Identifiers
  • (16β)-21-Chloro-9-fluoro-16-methyl-3,11,20-trioxopregna-1,4-dien-17-yl butyrate
CAS Number
ChemSpider
UNII
CompTox Dashboard (EPA)
ECHA InfoCard100.042.381
Chemical and physical data
FormulaC26H32ClFO5
Molar mass478.99 g·mol−1
3D model (JSmol)
  • CCCC(=O)O[C@@]1([C@H](C[C@@H]2[C@@]1(CC(=O)[C@]3([C@H]2CCC4=CC(=O)C=C[C@@]43C)F)C)C)C(=O)CCl
  • InChI=1S/C26H32ClFO5/c1-5-6-22(32)33-26(21(31)14-27)15(2)11-19-18-8-7-16-12-17(29)9-10-23(16,3)25(18,28)20(30)13-24(19,26)4/h9-10,12,15,18-19H,5-8,11,13-14H2,1-4H3/t15-,18-,19-,23-,24-,25-,26-/m0/s1
  • Key:FBRAWBYQGRLCEK-AVVSTMBFSA-N

Clobetasone butyrate is a synthetic glucocorticoid corticosteroid and a corticosteroid ester that is used in the treatment of skin disorders such as eczema and psoriasis.[1]

References

  1. ^ Goustas P, Cork MJ, Higson D (June 2003). "Eumovate (clobetasone butyrate 0.05%) cream: a review of clinical efficacy and safety". The Journal of Dermatological Treatment. 14 (2): 71–85. doi:10.1080/09546630310004180. PMID 12775314.
This article is issued from Wikipedia. The text is available under Creative Commons Attribution-Share Alike 4.0 unless otherwise noted. Additional terms may apply for the media files.