Clifford P. Brangwynne
Clifford P. Brangwynne | |
|---|---|
| Born | April 24, 1978 Boston, Massachusetts, USA |
| Alma mater | Carnegie Mellon University Harvard University |
| Scientific career | |
| Fields | Soft-matter physics, cell biology |
| Institutions | Princeton University |
Clifford P. Brangwynne is an American bioengineer, biophysicist and pioneer in the study of biomolecular condensates. Brangwynne is a professor of chemical and biological engineering at Princeton University, the director of the Omenn-Darling Bioengineering Institute, and the June K. Wu ’92 Professor in Engineering.[1] He is also a researcher at the Howard Hughes Medical Institute.[2]
Education
Brangwynne graduated from Carnegie Mellon University in 2001 with a degree in materials science and engineering, and received his Ph.D. in applied physics from Harvard University in 2007.[3] He served as a postdoctoral fellow from 2007 to 2010 at the Max Planck Institute of Molecular Cell Biology and Genetics, working with his adviser Anthony Hyman.[4]
Career
In 2009, Brangwynne discovered that cellular structures known as P granules dissolved and condensed in their surrounding cytoplasm through a process of liquid-liquid phase separation, with no confining membrane, overturning long-held assumptions about the nature of organelles.[5] In 2012, liquid-liquid phase separation was linked to neurodegenerative diseases such as ALS and Alzheimer’s. In 2017, it was linked to gene regulation.[6]
Brangwynne joined the Princeton faculty in 2011 as an assistant professor of chemical and biological engineering. At the time he was hired, the P granules paper had fewer than 10 citations; it has since accumulated more than 3,300.[7] He was promoted to associate professor in 2017 and to full professor in 2019. In 2020, he was named the June K. Wu ’92 Professor of Chemical and Biological Engineering and director of the Princeton Bioengineering Initiative, renamed the Omenn-Darling Bioengineering Institute in 2023.[4]
Awards
- 2025 – Kyoto University Lectureship Award
- 2025 – Keio Medical Science Prize[8]
- 2025 – Clarivate Citation Laureate[9]
- 2024 – CMU Alumni Achievement Award[10]
- 2023 – Dickson Prize in Medicine[11]
- 2023 – Breakthrough Prize in Life Sciences[12][13]
- 2022 – Tsuneko & Reiji Okazaki Award[14]
- 2021 – HFSP Nakasone Award[15][16]
- 2021 – Wiley Prize in Biomedical Sciences[17]
- 2020 – Blavatnik Awards for Young Scientists[18]
- 2020 – Michael and Kate Bárány Award[19]
- 2018 and 2019 – Finalists for Blavatnik Awards for Young Scientists[20]
- 2018 – MacArthur Fellowship[21]
- 2014 – Sloan Research Fellowship[22]
- 2013 – National Science Foundation CAREER Award[23]
- 2012 – NIH Director's New Innovator Award[24]
- 2012 – Searle Scholars Program[25]
- 2008–2010 – Fellow of Helen Hay Whitney Foundation[26]
References
- ^ "Clifford P. Brangwynne". Chemical and Biological Engineering, Princeton University. Retrieved 27 November 2022.
- ^ "Clifford P. Brangwynne". Howard Hughes Medical Institute. Retrieved 27 November 2022.
- ^ "CBE professor Clifford Brangwynne earns Breakthrough Prize in revolutionary cellular research". The Daily Princetonian. Retrieved 2 June 2023.
- ^ a b Brangwynne, Clifford. "Soft Living Matter group" (PDF). Soft Living Matter group.
- ^ Brangwynne, Clifford P.; Hyman, Anthony A. (21 May 2009). "Germline P Granules Are Liquid Droplets That Localize by Controlled Dissolution/Condensation". Science. 324 (5935): 1729–1732. doi:10.1126/science.1172046.
- ^ Lyon, Scott (22 September 2022). "Brangwynne wins the Breakthrough Prize for revolutionary view of living cells". Princeton Engineering.
- ^ https://scholar.google.com/citations?user=wAoRV_AAAAAJ&hl=en
- ^ Keio Medical Science Prize 2025
- ^ Keio Clarivate Citation Laureate 2025
- ^ CMU Alumni Achievement Award 2024
- ^ Dickson Prize 2023
- ^ "WINNERS OF THE 2023 BREAKTHROUGH PRIZES IN LIFE SCIENCES, MATHEMATICS AND FUNDAMENTAL PHYSICS ANNOUNCED". Breakthrough Prize. Retrieved 27 November 2022.
- ^ "Life Sciences Breakthrough Prize Laureates – Clifford P. Brangwynne". breakthroughprize.org. Retrieved 13 December 2024.
- ^ Tsuneko & Reiji Okazaki Award
- ^ "HFSP Nakasone Awardees". Human Frontier Science Program.
- ^ "Human Frontier Science Program awards Anthony Hyman and Clifford Brangwynne the 2021 HFSP Nakasone Award". Human Frontier Science Program.
- ^ "Biomedical Sciences | Prize". www.wiley.com. Retrieved 27 November 2022.
- ^ "Honorees". Blavatnik Awards for Young Scientists. Retrieved 27 November 2022.
- ^ "Clifford P. Brangwynne to Receive 2020 Michael and Kate Bárány Award". The Biophysical Society. Retrieved 27 November 2022.
- ^ "National Finalists". Blavatnik Awards for Young Scientists. Retrieved 27 November 2022.
- ^ "All Fellows". MacArthur Foundation. Retrieved 27 November 2022.
- ^ "Alfred P. Sloan Research Fellowships 2014" (PDF). Massachusetts Institute of Technology.
- ^ "Brangwynne Receives NSF CAREER Award". Princeton University. Retrieved 27 November 2022.
- ^ "NIH Director's New Innovator Award Program – 2012 Award Recipients". National Institutes of Health. 18 September 2018. Archived from the original on 17 April 2019. Retrieved 27 November 2022.
- ^ "Brangwynne Named Searle Scholar". Princeton University. Retrieved 27 November 2022.
- ^ "Clifford Paul Brangwynne" (PDF). Princeton University. Archived from the original (PDF) on 26 September 2022. Retrieved 27 November 2022.