Cetrimide

Cetrimide
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Identifiers
  • Compounds
  • Cetrimide: Mixture of
  • C12: Dodecyltrimethylammonium bromide
  • C14: Tetradecyltrimethylammonium bromide
  • C16: Hexadecyltrimethylammonium bromide
3D model (JSmol)
ChEBI
ChEMBL
ChemSpider
ECHA InfoCard 100.118.908
EC Number
  • Cetrimide: 617-073-5
  • C12: 214-290-3
  • C14: 214-291-9
  • C16: 200-311-3
KEGG
UNII
  • C12: InChI=1S/C15H34N.BrH/c1-5-6-7-8-9-10-11-12-13-14-15-16(2,3)4;/h5-15H2,1-4H3;1H/q+1;/p-1
    Key: XJWSAJYUBXQQDR-UHFFFAOYSA-M
  • C14: InChI=1S/C17H38N.BrH/c1-5-6-7-8-9-10-11-12-13-14-15-16-17-18(2,3)4;/h5-17H2,1-4H3;1H/q+1;/p-1
    Key: CXRFDZFCGOPDTD-UHFFFAOYSA-M
  • C16: InChI=1S/C19H42N.BrH/c1-5-6-7-8-9-10-11-12-13-14-15-16-17-18-19-20(2,3)4;/h5-19H2,1-4H3;1H/q+1;/p-1
    Key: LZZYPRNAOMGNLH-UHFFFAOYSA-M
  • C12: CCCCCCCCCCCCCC[N+](C)(C)C.[Br-]
  • C14: CCCCCCCCCCCCCCCC[N+](C)(C)C.[Br-]
  • C16: CCCCCCCCCCCCCCCCCC[N+](C)(C)C.[Br-]
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
Infobox references

Cetrimide, or alkyltrimethylammonium bromide, is an antiseptic which is a mixture of three quaternary ammonium compounds: tetradonium bromide (TTAB or MITMAB), cetrimonium bromide (CTAB), and laurtrimonium bromide (DTAB or LTAB).[1] It was first discovered and developed by ICI and introduced under the brand name Cetavlon.[2] It is used as a 1-3 % solution for cleaning roadside accident wounds.[3] ICI also introduced Savlon, which was a combination of cetrimide and chlorhexidine. ICI sold the Savlon brand OTC to Johnson & Johnson in May 1992.[4] Cetrimide is used in various applications such as antiseptic agents, diagnostic test and analysis, topical formulations, and dental treatment.[5]

References

  1. ^ Council of Europe (2007). European Pharmacopoeia (Ph. Eur.) (6.0 ed.). Strasbourg: The Stationery Office. pp. 1484–5. ISBN 978-92-871-6054-6. OCLC 170932841.
  2. ^ "Newspaper Article – Page 11 Advertisements Column 1". Archived from the original on 2013-10-05. Retrieved 2013-08-15.
  3. ^ Tripathi, KD. Essentials of Medical Pharmacology (7th ed.). p. 900.
  4. ^ "Johnson & Johnson acquires Savlon OTC brands from ICI – Free Online Library". Archived from the original on 2013-10-05.
  5. ^ "Cetrimide Applications". Novo Nordisk Pharmatech. 22 October 2021. Archived from the original on 2019-04-05.



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