Benfuresate

Benfuresate
Identifiers
CAS Number	68505-69-1;
3D model (JSmol)	Interactive image;
ChEBI	CHEBI:81756;
ChEMBL	ChEMBL2252194;
ChemSpider	2298853;
ECHA InfoCard	100.064.458
EC Number	270-925-4;
KEGG	C18452;
PubChem CID	3034378;
UNII	5E3V59Y698;
CompTox Dashboard (EPA)	DTXSID8058160 ;
	InChI InChI=1S/C12H16O4S/c1-4-17(13,14)16-9-5-6-11-10(7-9)12(2,3)8-15-11/h5-7H,4,8H2,1-3H3 Key: QGQSRQPXXMTJCM-UHFFFAOYSA-N;
	SMILES CCS(=O)(=O)OC1=CC2=C(C=C1)OCC2(C)C;
	Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa). Infobox references

Benfuresate is a herbicide belonging to the group of benzofurans.^[1]

Properties

Studies on zebrafish have shown that benfuresate inhibits embryonic growth in this species and can induce malformations. These findings underscore the risks that herbicide exposure poses to aquatic organisms.^[1]

Uses

Benfuresate is widely used post-emergence to control grasses and weeds, for example in rice, fruit, bean, corn and sugarcane cultivation. Before crop emergence, it is applied to cotton and tobacco plants.^[2]

Benfuresate controls cyperus rotundus in cotton. Young shoots appear to be more sensitive to benfuresate than the roots. While treatment of the leaves with benfuresate has little effect, it causes severe damage to the treated bud.^[3]

Authorization

In the EU and Switzerland, crop protection products containing the active ingredient benfuresate are no longer authorized.

Benfuresate was authorized for use on cotton plants in Spain.^[4]

Trade names

Cyperal, Morlene, Zerbex^[5]

References

^ ^a ^b Jin-Young Lee, Hahyun Park, Whasun Lim, Gwonhwa Song (2021-02-01), "Benfuresate induces developmental toxicity in zebrafish larvae by generating apoptosis and pathological modifications", Pesticide Biochemistry and Physiology, vol. 172, doi:10.1016/j.pestbp.2020.104751, PMID 33518044{{citation}}: CS1 maint: multiple names: authors list (link)
^ T. Roberts, D. Hutson, P. Lee, P. Nicholls, J. Plimmer (1998), "Herbicides and Plant Growth Regulators", Metabolic Pathways of Agrochemicals, vol. 1, Cambridge, pp. 133–134, ISBN 978-1-84755-138-2{{citation}}: CS1 maint: multiple names: authors list (link)
^ A. Fishler, J. C. Caseley, Rina Varsano, M. Negbi, B. Rubin (2006-07-28), "Factors affecting benfuresate activity against purple nutsedge (Cyperus rotundas L.)", Weed Research, vol. 35, no. 4, pp. 279–287, doi:10.1111/j.1365-3180.1995.tb01790.x{{citation}}: CS1 maint: multiple names: authors list (link)
^ D. Byrne. "VERORDNUNG (EG) Nr. 2076/2002 DER KOMMISSION vom 20. November 2002". Amtsblatt der Europäischen Gemeinschaften. Retrieved 2022-06-14.
^ Entry on Benfuresat. at: Römpp Online. Georg Thieme Verlag, retrieved {{{Datum}}}.

[Lee-1] Jin-Young Lee, Hahyun Park, Whasun Lim, Gwonhwa Song (2021-02-01), "Benfuresate induces developmental toxicity in zebrafish larvae by generating apoptosis and pathological modifications", Pesticide Biochemistry and Physiology, vol. 172, doi:10.1016/j.pestbp.2020.104751, PMID 33518044{{citation}}: CS1 maint: multiple names: authors list (link)

[Robert-2] T. Roberts, D. Hutson, P. Lee, P. Nicholls, J. Plimmer (1998), "Herbicides and Plant Growth Regulators", Metabolic Pathways of Agrochemicals, vol. 1, Cambridge, pp. 133–134, ISBN 978-1-84755-138-2{{citation}}: CS1 maint: multiple names: authors list (link)

[3] A. Fishler, J. C. Caseley, Rina Varsano, M. Negbi, B. Rubin (2006-07-28), "Factors affecting benfuresate activity against purple nutsedge (Cyperus rotundas L.)", Weed Research, vol. 35, no. 4, pp. 279–287, doi:10.1111/j.1365-3180.1995.tb01790.x{{citation}}: CS1 maint: multiple names: authors list (link)

[4] D. Byrne. "VERORDNUNG (EG) Nr. 2076/2002 DER KOMMISSION vom 20. November 2002". Amtsblatt der Europäischen Gemeinschaften. Retrieved 2022-06-14.

[Römpp-5] Entry on Benfuresat. at: Römpp Online. Georg Thieme Verlag, retrieved {{{Datum}}}.

[1]

[2]

[3]

[4]

[5]