3-methylbutanal reductase
| 3-methylbutanal reductase | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifiers | |||||||||
| EC no. | 1.1.1.265 | ||||||||
| Databases | |||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB structures | RCSB PDB PDBe PDBsum | ||||||||
| Gene Ontology | AmiGO / QuickGO | ||||||||
| |||||||||
In enzymology, 3-methylbutanal reductase (EC 1.1.1.265) is an enzyme that catalyzes the chemical reaction
The two substrates of this enzyme are isoamyl alcohol (3-methylbutan-1-ol) and oxidised nicotinamide adenine dinucleotide (NAD+). Its products are isovaleraldehyde (3-methylbutanal), reduced NADH, and a proton. The enzyme can also use the alternative cofactor, nicotinamide adenine dinucleotide phosphate[1][2]
This enzyme belongs to the family of oxidoreductases, specifically those acting on the CH-OH group of donor with NAD+ or NADP+ as acceptor. The systematic name of this enzyme class is 3-methylbutanol:NAD(P)+ oxidoreductase.
References
- ^ Enzyme 1.1.1.265 at KEGG Pathway Database.
- ^ van Iersel MF, Eppink MH, van Berkel WJ, Rombouts FM, Abee T (1997). "Purification and characterization of a novel NADP-dependent branched-chain alcohol dehydrogenase from Saccharomyces cerevisiae". Appl. Environ. Microbiol. 63 (10): 4079–82. Bibcode:1997ApEnM..63.4079V. doi:10.1128/aem.63.10.4079-4082.1997. PMC 168719. PMID 9327572.