3''-deamino-3''-oxonicotianamine reductase

3″-deamino-3″-oxonicotianamine reductase
Identifiers
EC no.1.1.1.285
Databases
IntEnzIntEnz view
BRENDABRENDA entry
ExPASyNiceZyme view
KEGGKEGG entry
MetaCycmetabolic pathway
PRIAMprofile
PDB structuresRCSB PDB PDBe PDBsum
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In enzymology, 3''-deamino-3''-oxonicotianamine reductase (EC 1.1.1.285) is an enzyme that catalyzes the chemical reaction

2'-deoxymugineic acid
 
 
 
H+
 
H+
 
3"-deamino-3"-oxonicotianamine
 

The two substrates of this enzyme are 2'-deoxymugineic acid and oxidised nicotinamide adenine dinucleotide (NAD+). Its products are 3''-deamino-3''-oxonicotianamine, reduced NADH, and a proton. This enzyme can also use the alternative cofactor, nicotinamide adenine dinucleotide phosphate.[1][2]

This enzyme belongs to the family of oxidoreductases, specifically those acting on the CH-OH group of donor with NAD+ or NADP+ as acceptor. The systematic name of this enzyme class is 2-deoxymugineic acid:NAD(P)+ 3-oxidoreductase.

References

  1. ^ Enzyme 1.1.1.285 at KEGG Pathway Database.
  2. ^ Shojima S, Nishizawa NK, Fushiya S, Nozoe S, Irifune T, Mori S (August 1990). "Biosynthesis of Phytosiderophores : In Vitro Biosynthesis of 2'-Deoxymugineic Acid from l-Methionine and Nicotianamine". Plant Physiology. 93 (4): 1497–503. doi:10.1104/pp.93.4.1497. PMC 1062701. PMID 16667646.