2-alkyn-1-ol dehydrogenase
| 2-alkyn-1-ol dehydrogenase | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifiers | |||||||||
| EC no. | 1.1.1.165 | ||||||||
| CAS no. | 54576-94-2 | ||||||||
| Databases | |||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB structures | RCSB PDB PDBe PDBsum | ||||||||
| Gene Ontology | AmiGO / QuickGO | ||||||||
| |||||||||
In enzymology, 2-alkyn-1-ol dehydrogenase (EC 1.1.1.165) is an enzyme that catalyzes the chemical reaction below:
The two substrates of this enzyme are 1,4-butynediol and oxidised nicotinamide adenine dinucleotide (NAD+). Its products are 4-hydroxybut-2-ynal, reduced NADH, and a proton.[1]
This enzyme belongs to the family of oxidoreductases, specifically those acting on the CH-OH group of donor with NAD+ or NADP+ as acceptor. The systematic name of this enzyme class is 2-butyne-1,4-diol:NAD+ 1-oxidoreductase.[2]
References
- ^ Enzyme 1.1.1.165 at KEGG Pathway Database.
- ^ Miyoshi T, Sato H, Harada T (1974-08-26). "Purification and characterization of 2-alkyne-1-ol dehydrogenase induced by 2-butyne-1,4-diol in Fusarium merismoides B11". Biochimica et Biophysica Acta (BBA) - Enzymology. 358 (2): 231–239. doi:10.1016/0005-2744(74)90452-5. ISSN 0005-2744.